The performance of the 20- and the 64-channel head coil and the influence of the prescan normalize filter was evaluated in a standard fMRI setting using a 3T Siemens Prisma MRI. Larger beta estimates and tSNR occurred in auditory cortex and thalamus with prescan normalize, in contrast to the visual and motor cortex with larger beta estimates and tSNR without prescan normalize. In line with the results of the MRIQC tool, the 20-channel head coil with prescan normalize is better suitable for functional measurements, especially in deeper brain areas. The 64-channel head coil is the best choice for anatomical scans.
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