The tissue composition of carotid atherosclerotic plaques is crucial for cardiovascular risk assessment and can be quantified with high-resolution multi-contrast MRI by expert reviewers. The purpose of this work is to develop AI-CASCADE, a fully automated solution for quantitative analysis of carotid MRI, including artery localization, vessel wall segmentation, artery registration and plaque component segmentation. Results in our preliminary study show that AI-CASCADE achieves good agreements with manual results and has great potential as an efficient and reliable clinical tool.
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