Cryogenically cooled transmit/receive
radiofrequency coils (cryocoils) improve the signal-to-noise ratio (SNR) compared
to conventional RF coils by minimizing thermal coil noise. The SNR of a cryoprobe, a surface coil at
room temperature and a volume coil was assessed using chemical shift imaging of
a 13C-urea phantom. Using the
cryocoil an SNR improvement up to a factor of 10 compared to
conventional coils was observed. In addition, a proof-of-concept in vivo
experiment using the 13C-cryocoil for detection of the metabolic
turnover of hyperpolarized 13C-pyruvate was successfully performed.
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