Abstract #2359

An investigation of the change in water diffusivity along the perivascular space in hypertensive patients

Junko Kikuta¹, Koji Kamagata¹, Kaito Takabayashi¹, Toshiaki Taoka², Hajime Yokota³, Yuki Someya⁴, Yoshifumi Tamura^4,5, Hirotaka Watada^4,5, Ryuzo Kawamori^4,5, Shinji Naganawa⁶, and Shigeki Aoki¹

¹Department of Radiology, Juntendo University School of Medicine, Bunkyo-ku, Japan, ²Department of Innovative Biomedical Visualization, Graduate School of Medicine, Nagoya University, Nagoya, Japan, ³Department of Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, ⁴Sportology Center, Juntendo University School of Medicine, Bunkyo-ku, Japan, ⁵Department of Metabolism & Endocrinology, Juntendo University School of Medicine, Bunkyo-ku, Japan, ⁶Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan

We used the analysis along the perivascular space (ALPS) index, which has been suggested as a noninvasive method to measure water diffusivity along the perivascular space in vivo. We assessed the change in water diffusivity in living patients with hypertension for the first time.

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