Abstract #2344

DKI for Assessing the Therapeutic Response of TACE in Hepatocellular Carcinoma and Invasion of Peritumoral Zone

Junying wang¹, Weiqiang Dou², Xiaoyi He³, and Hao Shi⁴

¹Medical Imaging, Shandong Provincial Qianfoshan Hospital, the First Hospital Affiliated with Shandong First Medical University, Jinan, China, ²GE Healthcare, MR Research China, Bejing,, Beijing, China, ³Medical Imaging, Shandong Provincial Qianfoshan Hospital, the First Hospital Affiliated with Shandong First Medical University, Jinan, Shandong, China, ⁴Shandong Provincial Qianfoshan Hospital, the First Hospital Affiliated with Shandong First Medical University, Jinan, Shandong, China

Diffusion kurtosis imaging (DKI) is able to describe the deviations of water molecules diffusion from Gaussian form and depict the microstructural environment precisely. Previous study applied DKI in assessing the therapeutic response of Transcatheter Arterial Chemoembolization (TACE) in Hepatocellular Carcinoma (HCC), and showed promising results. On this basis, this study further explored the clinical value of DKI in assessing liver cancer and tumoral cell invasion of peritumoral zone between HCC progressive group and pseudo-progressive group after TACE treatment, in order to provide new ideas for clinical follow-up.

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