Susceptibility weighted imaging (SWI) has shown tremendous clinical potential in visualizing the micro-haemorrhage, calcification, neovascularization and so forth, which serve as important micro-structural manifestations during the carcinogenesis. Radiomics is of great significance for providing valuable quantitative image markers via high throughput feature extraction. However, hardly have the radiomics been applied for extracting the quantitative markers from SWI images. This research, hence, aims to extract the diagnostic markers from the SWI images for evaluating several important prognostic markers of hepatocellular carcinoma including histopathologic grade, microvascular invasion (MVI) as well as the expression status of cytokeratin 7, cytokeratin 19 and Glypican-3.
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