Prediction of growth potential in the pediatric population is critical to trace therapies targeting growth deficiencies and to inform surgical planning. Clinical models to predict growth potential are very inaccurate. We aim to validate DTI of the physis and metaphysis (DTI-P/M) as a prediction biomarker of growth potential in children. We compared in a cohort of 90 children the prediction accuracy of DTI-P/M and clinical models. Our data showed that DTI-P/M predicted growth potential more accurately than clinical models (over 40% reduction in error). Even more importantly, compared to clinical models DTI-MP predictions did not show any prediction bias.
This abstract and the presentation materials are available to members only; a login is required.