The present study provides initial evidence indicating that a higher risk of EXD is linked with a smaller GMV in the right OFC, left sgCG, and left IPL in a sample of regular exercisers, which sheds light on the neuroanatomical basis of EXD. Furthermore, our study found that the right OFC mediates the relationship between stress and EXD, revealing a potential neuropsychological mechanism for how stress affects EXD. Our findings might facilitate the diagnosis of EXD and the target selection for the corresponding intervention (e.g., behavioral or brain intervention ) to help individuals reduce EXD and improve their quality of life.
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