Abstract #1985

Simultaneous Water and Lipid Suppression Using Chemical Selective Adiabatic Refocusing Pulses Echo Planar Spectroscopic Imaging (EPSI) at 7T

Guodong Weng¹, Sulaiman Sheriff², Claus Kiefer¹, Irena Zubak³, Andrew A Maudsley², and Johannes Slotboom¹

¹Institute for Diagnostic and Interventional Neuroradiology, Support Center for Advanced Neuroimaging (SCAN), University of Bern, Bern, Switzerland, ²Department of Radiology, University of Miami School of Medicine, Miami, FL, United States, ³Inselspital Bern and University Hospital, Bern, Switzerland

To tackle the chemical shift displacement artifacts (CSDA), B1-inhomoheneity, water and fat suppression as well as specific absorption-rate (SAR) limitation at 7T spectroscopy, an EPSI-variant sequence is developed in this study. The conventional slice-selective refocusing pulse is replaced by a spectral-selective adiabatic 2π-pulse pair. The results show a 77% reduction of CSDA, homogeneous refocusing map, water suppression factor ≥ 1000 within an acceptable SAR both in vitro and in vivo measurement. The scan time for the whole brain is within 8 minutes. This new EPSI-variant sequence shows its high application potential clinical routine.

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