Abstract #1926

Correlation of gray matter thickness, gray matter volume, white matter lesion and clinical scoring in normal healthy elderly in Thailand

Tharathorn Kaeowirun¹, Chanon Ngamsombat¹, Doonyaporn Wongsawaeng ¹, Siriwan Piyapittayanan¹, Yudthaphon Vichianin², Weerasak Muangpaisan³, Panida Charnchaowanish¹, and Orasa Chawalparit¹

¹Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand, ²Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand, ³Department of Preventive and Social Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

A simple screening tool such as MoCA has been used for demonstrating cognitive change even in normal aging process. Brain MRI has been used to demonstrate the etiology of cognitive problem in elderly. Structural changes by both visual assessment and automated methods can be obtained using MR study. We demonstrated the differences of structural parameters including cortical thickness, volume and white matter lesions(nonspecific white matter change) with a clinical MoCA test in normal aging population.

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