Abstract #1743

Magnetic resonance fingerprinting in two-month-recovered COVID-19 patients

Yaping Wu¹, Xianchang Zhang², Yu Shen¹, Yan Bai¹, Wei Wei¹, Congyu Liao³, and Meiyun Wang¹

¹Department of Medical Imaging, Henan Provincial People’s Hospital & the People’s Hospital of Zhengzhou University, Zhengzhou, China, ²MR Collaboration, Siemens Healthcare Ltd., Beijing, China, ³Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States

This study investigated the utility of magnetic resonance fingerprinting (MRF) to detect potential brain changes in recovered COVID-19 patients. MRF T1 and T2 maps of the brains of 8 recovered COVID-19 patients and 8 volunteers were non-linearly normalized into the MNI space to explore the differences between the groups using whole-brain analysis. COVID-19 patients had significantly lower T1 and T2 values in the left superior temporal gyrus, near the hub for the olfaction and gustation systems, and other brain areas. Our findings suggest that SARS-CoV-2 may widely affect the neurological system, and the effect persisted after more than two months.

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