As a critical step to establish the Multichannel Illinois Institute of Technology & Rush university Aging (MIITRA) atlas, the present work aimed to: a) develop high quality 0.5mm resolution T1-weighted (T1w) and diffusion tensor imaging (DTI) templates in a common space using data from a large, diverse, community cohort of non-demented older adults, and b) quantitatively compare the new templates to existing templates in terms of spatial normalization accuracy of external data. The new T1w and DTI templates allowed higher inter-subject and inter-modality spatial normalization of older adult data compared to other templates.
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