The purpose of this analysis is to investigate the patterns of individual rates of change of diffusion tensor imaging (DTI) measures computed from a longitudinal study of autism spectrum disorder (ASD). The mean value and temporal rates of change of DTI measures were estimated for regions of white matter for individual subjects. The distributions of the individual longitudinal slopes versus mean measures for ASD and typically developing controls (TDC) were mapped and compared, revealing group differences in the distributions with generally greater heterogeneity in the ASD group.
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