The purpuse of this study was to assess microvascular perfusion and microstructural integrity using Intravoxel incoherent motion (IVIM) imaging in patients with acute CO poisoning.Thirteen patients with acute CO poisoning and 15 healthy subjects were enrolled. IVIM MRI was collected using a 3.0-T scanner.The ROIs analysis was perforemed. The IVIM perfusion fraction was significantly reduced in multiple brain regions and IVIM diffusion metirc was significantly decreased in centrum semiovale and multiple subcortical gray matter nucleis in CO poisoning. This study shows that IVIM-DWI may be a promising method to assess brain perfusion and injury in acute CO poisoning.
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