Amide proton transfer-weighted (APTw) imaging can be used to assess changes of intracellular protein concentration and the pH value. Non-invasive visualization and quantification of tissue composition could be detected by T1 map. In this study, we aim to explore the value in difference of rectal cancer with and without lymph node metastasis using APTw imaging combined with T1 map. High diagnostic efficacy (AUC: 0.891; sensitivity: 81.8%; specificity: 100.0%) was achieved with combination of APT and T1 values.
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