The aim of the study was to compare intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) for evaluating lung cancer using single-shot gradient- and spin-echo (SS-GRASE), single-shot turbo spin-echo (SS-TSE) and single-shot echo-planar imaging (SS-EPI) on a 3.0T MRI scanner. The signal-to-noise ratio (SNR), contrast signal-to-noise ratio (CNR), image distortion of lesions, ADC and IVIM parameters from the three sequences were compared. We found that GRASE-IVIM had the characteristics of short scan time and small distortion, relatively low SNR but high CNR. Our study showed that GRASE-IVIM has great potential for lung cancer.
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