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Abstract #1291

3D Quantitative MRI of the Brain: Effects of B1 Inhomogeneity in 3D-QALAS

Anders Tisell1,2, Peter Lundberg1,2, Marcel Jan Bertus Warntjes1, and Frederik Testud3
1CMIV, Linköping University, Linköping, Sweden, 2Medical Radiation Physics, Linköping University, Linköping, Sweden, 3Siemens Healthcare AB, Malmö, Sweden

We have implemented the 3D QALAS sequence for a 3 T MR-scanner and validated the accuracy and evaluated the effect of B1+ inhomogeneities on the resulting R1 and R2 estimations. When using a small flip angle of 4° the determined R1 and R2 maps showed a high accuracy; however, for 10° there was a significant bias and dependence on B1+ inhomogeneities.

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