Identification of MR imaging biomarkers for solid tumors requires a reliable means of correlating multiparametric MR and pathological data. We have constructed a platform for registration of multi-scale preclinical imaging libraries that utilizes MR histology and cytometric feature mapping for correlative studies. With this platform we have identified a selection of cytometric features in murine sarcomas which demonstrate correlative trends with ex vivo and in vivo MR, including ADC and T2*.
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