This study aimed to shorten acquisition time of RESOLVE-based diffusion kurtosis imaging (DKI) in nasopharyngeal carcinoma (NPC), and we explored the influence of b value combinations on the scan time and parameters from DKI. The results showed that the group with b-value (200, 400, 800, 2000) had excellent agreement with the actual acquisition with b-value (200, 400, 800, 1500, 2000) and the scan time saved 28% (3min46s vs 5min13s), and was recommended in the clinical DKI research in NPC.
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