Abstract #0844

Analysis of Diffusion Changes in Patients with Juvenile Osteochondritis Dissecans (JOCD) of the Knee at 3T

Abdul Wahed Kajabi^1,2,3, Stefan Zbyn^1,3, Cyrus M. Nouraee¹, Kai D. Ludwig^1,3, Casey P. Johnson^1,4, Steen Moeller¹, Mark A. Tompkins⁵, Bradley J. Nelson⁵, Gregory J. Metzger¹, Cathy S. Carlson⁴, and Jutta M. Ellermann^1,3

¹Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, ²Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, ³Department of Radiology, University of Minnesota, Minneapolis, MN, United States, ⁴Department of Veterinary Clinical Sciences, University of Minnesota, Minneapolis, MN, United States, ⁵Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, United States

This 3T study evaluates 46 juvenile osteochondritis dissecans (JOCD) lesions of 41 skeletally immature patients using clinical, morphological MRI and diffusion-weighted MRI (DWI). In this study, apparent diffusion coefficient (ADC) values were able to differentiate between healed and not yet healed JOCD lesions, and distinguish between the operative and nonoperative treatment groups. DWI provides noninvasive, quantitative assessment of disease status which may help inform clinical management of JOCD. Further follow-up studies are needed to evaluate the potential of DWI for the prediction of lesion healing in JOCD patients.

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