Abstract #0775

3D APTw Brain Tumor Imaging with Compressed SENSE: Comparison of Different Acceleration Factors and with Conventional Parallel Imaging

Nan Zhang¹, Qingwei Song², Ailian Liu², Haonan Zhang², Renwang Pu², Jiazheng Wang³, and Zhiwei Shen³

¹The First Affilliated Hospital of Dalian Medical University, Dalian, China, ²The First Affiliated Hospital of Dalian Medical University, Dalian, China, ³Philips Healthcare, Beijing, China, Beijing, China

Amide proton transfer weighted (APTw) imaging is a novel and promising MRI method for brain tumor imaging, but it can be time-consuming. Common parallel imaging methods, like SENSE, can lead to reduced image quality and increased artifact at high acceleration factors. Here, the compressed SENSE (CS) technique with combined strength from both compressed sensing and SENSE was evaluated for the acceleration of APTw imaging in brain. Results showed that it is feasible to apply an CS accelerator factor of 5 to APTw imaging of brain tissue and tumor, which could reduce the scan time to less than 1 min.

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