The use of texture analysis in clinical images can provide surrogate information on tumor microenvironment and predict the prognosis of patients. In this study, we evaluate the utility of texture analysis of tumor ADC values to predict the overall survival in patients with pancreatic cancer and to correlate with pathological evaluated massive intratumoral necrosis. Our results showed that the kurtosis of tumor ADC values obtained from texture analysis is correlated with massive intratumoral necrosis and is associated with poor prognosis in patients with pancreatic cancer.
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