Abstract #0248

Fast MR thermometry based on propeller echo‐planar time‐resolved imaging with dynamic encoding (PEPTIDE)

Zhehong Zhang¹, Fair Merlin², Fuyixue Wang^3,4, Zijing Dong^3,5, Wending Tang¹, Menghan Li¹, Danna Wei⁶, Kawin Setsompop^2,7, and Kui Ying¹

¹Department of Engineering Physics, Tsinghua University, Beijing, China, ²Department of Radiology, School of Medicine, Stanford University, Stanford, CA, United States, ³Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ⁴Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, ⁵Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, ⁶Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ⁷Department of Electrical Engineering, Stanford University, Stanford, CA, United States

Echo‐planar time‐resolved imaging (EPTI) is a multi-shot EPI technique capable of rapidly obtaining distortion‐free and blurring‐free time-resolved multi-contrast images across the EPI readout. PROPELLER is an extension to EPTI, which incorporates PROPRELLER-like acquisition, to enable shot-to-shot motion toleration. In this work, PEPTIDE was applied to the MR thermometry application, where an image reconstruction framework that leveraged sparsity across blades of PEPTIDE rawdata was proposed. The potential in using PEPTIDE to provide distortion- and blurring-free temperature mapping at high temporal resolution was then demonstrated via simulated human brain PEPTIDE data with various temperature profiles.

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