The aim of this study was to investigate the feasibility of intratumoral susceptibility signal intensities (ITSS) combined with R2* values obtained from T2 star-weighted angiography (ESWAN) in quantitatively and automatically evaluating histological grading of hepatocellular carcinoma (HCC). The results showed that the combination of quantitative ITSS and R2* was feasible to evaluate the histological grading of HCC performance (AUC = 0.856, P < 0.0001, sensitivity of 88.89%, specificity of 69.44%) automatically.
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