White matter microstructural abnormalities are well documented in HIV-infected individuals. DTI derived fractional anisotropy (FA) is frequently used to assess the abnormalities but it has some limitations. In this work, we compared FA and microscopic fractional anisotropy (μFA) in an HIV cohort, and our results indicate that μFA seems to provide better sensitivity than the conventional FA for detecting white matter microstructure changes associated with HIV infection, especially in the areas with crossing fibers.
This abstract and the presentation materials are available to members only; a login is required.