Abstract #4858

Texture analyses based on multiple high b-value diffusion-weighted imaging (DWI) for evaluation of tumor heterogeneity in prostate cancer

Jingjun Wu¹, Ailian Liu¹, Jiazheng Wang², Liangjie Lin², Lihua Chen¹, Qingwei Song¹, Renwang Pu¹, and Bingbing Gao¹

¹Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

In the current study, multiple high b-value DWI-based texture analysis was applied to evaluate tumor heterogeneity in prostate cancer patients. Parameters, including MinIntensity, MedianIntensity, MeanValue, and Skewnesswere were significantly different among DWI images with different b values. Therefore, texture analysis based on DWI maps with different b values may serve as a preoperative and non-invasive method for evaluating heterogeneity of prostate cancer.

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