Current methodology in analyzing pathological lymph node radiotherapy response in head and neck cancer relies on qualitative visual inspection of geometrical features. A quantitative approach that takes into account dynamic changes in underlying lymph node pathology could be an important supplemental clinical tool in radiotherapy treatment planning. Herein, we investigate dynamic contrast enhanced MRI quantitative parametric maps as possible biomarker candidates for lymph node radiotherapy response by analyzing multi-timepoint images of head and neck cancer patients.
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