Genes play a crucial role in the development, progression and therapeutic outcome of tumors. Several studies have linked codeletion of chromosomal arms 1p/19q in LGG with positive response to chemotherapy and radiotherapy and longer progression-free survival, so 1p/19q status of LGG can impact optimal therapy options. Unfortunately, determining 1p/19q status requires surgical biopsy to identify chromosomal deletion. Radiomics, which extracts high-throughput features from medical images, showing great advantages in tumor phenotype classification, treatment options and prognosis analysis.
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