In the study, the relationship between three brain regions (brain metastasis, normal brain region and perituberous edema region) and radiotherapy dose gradient has been explored. 3D arterial spin labeling perfusion imaging (3D-ASL) for quantitative cerebral blood flow measurement has been used in the clinical diagnosis, preoperative differentiation and grading of brain tumors. Therefore, individualized radiotherapy for BM patients could be optimized and improve the local control rate of BM.
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