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Abstract #4743

Biomechanical Response of Orthotopic Pancreatic Tumours to the Vascular Disrupting Agent ZD6126 Assessed by Magnetic Resonance Elastography

Jin Li1, Emma L. Reeves1, Jessica K.R. Boult1, Craig Cummings1, Jeffrey C. Bamber1, Ralph Sinkus2, Yann Jamin1, and Simon P. Robinson1
1Division of Radiotherapy & Imaging, The Institute of Cancer Research, London, United Kingdom, 2Division of Imaging Sciences and Biomedical Engineering, King's College London, King’s Health Partners, St. Thomas’ Hospital, London, United Kingdom

MRE-derived shear stiffness |G*| of orthotopic pancreatic tumours was sensitive to a heterogeneous treatment response induced by the vascular disrupting agent ZD6126.

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