High-resolution DTI of ex vivo rat sciatic nerve yields viable biomarkers of peripheral nerve recovery following partial transection and surgical repair. FA values decreased with increasing cut depth at 4 weeks. By week 12, the three partial cuts showed elongated FA distributions, most likely representing regions with regenerated (high FA values) and degenerated axons (low FA values). FA finding are influenced by pathological features that affect diffusion both perpendicular and parallel to the axons.
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