Abstract #4467

Cortical projections of the superoanterior fasciculus (SAF)

Szabolcs David¹, Michel Thiebaut de Schotten², Fenghua Guo¹, Flavio Dell’Acqua³, Alexander Leemans¹, and Alberto de Luca¹

¹Image Sciences Institute, UMC Utrecht, Utrecht, Netherlands, ²Brain Connectivity and Behaviour Laboratory, Sorbonne Universities, Paris, France, ³NatBrainLab, Department of Forensics and Neurodevelopmental Sciences, Sackler Institute for Translational Neurodevelopment, King's College London, London, United Kingdom

The superoanterior fasciculus (SAF) is defined as a bilateral tract in the frontal lobe that resembles the structure of the anterior cingulum, but is located superior, anterior and lateral. In this work, we investigated the cortical projections of the structure utilizing the latest multi-shell multi tissue (MSMT) constrained spherical deconvolution (CSD) method to analyze diffusion MRI data from the Human Connectome Project (HCP). Our results show that the paracentral lobular, mid cingulate cortex and the orbital- and polar frontal cortex show high SAF termination prevalence, suggesting a novel connection in the frontal lobe.

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