Abstract #4319

Performance comparison of three b-value sampling schemes in multiple diffusion models, including DTI, DKI, NODDI and MAP-MRI

Huiting Zhang¹, Ankang Gao², Shaoyu Wang¹, Yang Song³, Jingliang Cheng², Guang Yang³, and Xu Yan¹

¹MR Scientific Marketing, Siemens Healthcare, Shanghai, China, ²The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ³Shanghai Key Laboratory of Magnetic Resonance, East China Normal Univeristy, Shanghai, China

This study aimed to evaluate the performance of three b-value sampling schemes in calculating multiple diffusion models, including the DTI, DKI, NODDI and the newly proposed mean apparent propagator (MAP)-MRI models. The three schemes includes the conventional diffusion spectrum imaging (DSI) acquisition scheme based on Cartesian grid sampling in q-space, multi-shell sampling with the same (MDDW) or different (FREE) gradient directions in each shell. Each scheme supports the estimation of all the four models. The results showed that generally three schemes generated very similar parameters, and could be all used in future studies.

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