In this study we compare SENSE accelerated multi-shot variable density spiral diffusion to the current clinical standards: single shot EPI and MultiVane TSE diffusion. A variable density sampling strategy was employed to correct for the phase of the different shots and iterative SENSE was used to reduce the number of shots and scanning duration. This technique was applied on a clinical platform with clinically acceptable reconstruction times. We showed that spiral diffusion reduces distortions in difficult to shim brain regions compared to ssh-EPI, and spiral diffusion has at a reduced scan duration compared to the TSE-based approach.
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