Abstract #4145

4D-MRI of Thorax and Abdomen with Variable Contrast at 1.5T

Orso Andrea Pusterla^1,2,3, Francesco Santini^2,3, Grzgorz Bauman^2,3, Rahel Heule⁴, Alina Giger³, Philippe Claude Cattin³, Sairos Safai⁵, Sebastian Kozerke¹, and Oliver Bieri^2,3

¹Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, ²Department of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland, ³Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland, ⁴High Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, ⁵Center for Proton Therapy, Paul Scherrer Institute, Villigen-PSI, Switzerland

Time-resolved volumetric imaging (4D-MRI) of moving organs is essential for several clinical applications, e.g., in interventional treatments, radiation therapies, and high-intensity focused ultrasound ablations. In this work, an interleaved time-resolved data-navigator acquisition strategy for 4D-MRI with flexible contrast is developed offering versatile settings for thoracic and abdominal imaging: for both, image and navigator, not only the flip angle but also the basic acquisition type (pulse sequence kernel) can be chosen independently from either balanced SSFP (i.e., T₂/T₁-weighted) or spoiled gradient echo (i.e., T₁-weighted).

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