Physiologic noise correction for phase shifted cardiac fluctuation with the quality assurance of measured and estimated physiologic noise.

We have previously developed and publicly shared the physiologic noise estimation and removal software package, PESTICA (www.nitrc.org/projects/pestica). We present a new version of the PESTICA/RETROICOR software package, correcting cardiac phase shift and generating the goodness of fit with modeled physiologic noise and quality assurance of external physiologic signals based AFNI and Matlab. This study describes the updates, validation and demonstrate its usage.