Abstract #3769

Quantitative and Synthetic MRI for Breast Assessment in Clinical Acquisition Times

Nina Pötsch¹, Marcus Raudner^1,2, Tom Hilbert^3,4,5, Tobias Kober^3,4,5, Elisabeth Weiland⁶, Panagiotis Kapetas¹, and Pascal Baltzer¹

¹Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ³Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, ⁴Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁵LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁶Siemens Healthcare GmbH, Erlangen, Germany

Contrast-enhanced breast MRI is the most sensitive tool for the detection of breast cancer. Contrast enhancement is however not specific to cancer: incidental benign findings regularly require further workup including ultimately avoidable follow-up scans and biopsies. Quantitative T1 and T2 measurements could be used as discriminative imaging markers to assist clinical decision-making. This feasibility study illustrates the potential clinical benefits of quantitative imaging for breast MRI by combining two fast and robust mapping techniques for high-resolution parameter mapping in a clinically feasible scan time of 7:32 min using prototype compressed sensing MP2RAGE and GRAPPATINI sequences with a harmonized protocol.

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