Abstract #3338

Quantitative abdominal imaging using 3D motion-robust MR fingerprinting

Max van Riel^1,2, Zidan Yu^2,3, Shota Hodono^2,3, Ding Xia², Hersh Chandarana², and Martijn A. Cloos^2,3

¹Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, ²Center for Advanced Imaging Innovation and Research and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, ³Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, United States

We demonstrate a 3D MR fingerprinting sequence for quantitative abdominal imaging. The sequence was made robust to motion by modifying the order of acquisition to allow for free-breathing imaging. Furthermore, the flip angle pattern was optimized using the Cramér-Rao Lower Bound to increase the efficiency of the sequence. A phantom was used to validate the new sequence and it was shown that the motion-robust ordering reduced motion-related artefacts. In vivo results showed reduced artefacts as well. We conclude that it is possible to generate B₁-robust quantitative T1 and proton density maps at a clinically usable resolution within 5 minutes.

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