Abstract #3313

Comparison of multi-platform 2D and 3D MR elastography in vivo and in vitro

Paul Kennedy^1,2, Daniel Stocker^1,2, Octavia Bane^1,2, Stefanie Hectors^1,2,3, Bradley D Bolster Jr. ⁴, and Bachir Taouli^1,2

¹BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Department of Radiology, Weill Cornell Medicine, New York, NY, United States, ⁴Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States

In this study we assess the variation in 2D and 3D MR elastography (MRE) measures in patients, volunteers and a phantom across two MR system vendors. Interobserver variability was also examined. 2D and 3D MRE liver measurements were not significantly different across systems and showed excellent intraclass correlation coefficient (ICC) between readers. Spleen measurement showed excellent ICC between readers but significant variation in 3D MRE spleen stiffness was found between systems. Liver 3D MRE is stable across platforms however further study is required to assess the bias in 3D MRE spleen measurements from multiple vendors.

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