MR elastography (MRE) requires acquisitions of multiple phase offset images. Patient movement between acquisitions of phase offset images is not only difficult to be detected, but also leads to calculate shear modulus incorrectly. To resolve this problem, we present a novel MRE technique that can acquire multiple phase offset images simultaneously (SAMURAI-MRE) using a motion-encoding gradient (MEG)-less multi-echo sequence. MRE images obtained at spin-echo (SE)- and gradient-echo (GRE)-based SAMURAI-MRE were compared with those at conventional SE- and GRE-based MEG-less multi-echo MRE. The results demonstrate that it is possible to perform SAMURAI-MRE, and SE-based SAMURAI-MRE was superior to GRE-based SAMURAI-MRE.
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