Abstract #3200

Improved signal modeling in Quantitative Susceptibility Mapping using multi-echo complex Total Field Inversion (mcTFI)

Yan Wen^1,2, Thanh Nguyen², Junghun Cho^2,3, Pascal Spincemaille², and Yi Wang^3,4

¹Meinig School of Biomedical Engineering, Cornell University, new york, NY, United States, ²Radiology, Weill Cornell Medicine, New York, NY, United States, ³Meinig School of Biomedical Engineering, Cornell University, New York, NY, United States, ⁴Radiology, Weill Cornell Medicine, new york, NY, United States

Multi-echo Complex Total Field Inversion (mcTFI) is a Total Field Inversion (TFI) method that computes QSM directly from the complex gradient echo data, for which the assumption of Gaussian noise is well justified. mcTFI demonstrated improvement over TFI in simulation and hemorrhage brain.

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