Abstract #3175

Effect of RF Pulse Duration on Chemical Shift Encoded MRI

Nathan Tibbitts Roberts^1,2, Timothy Colgan¹, and Scott B Reeder^1,3,4,5,6

¹Radiology, University of Wisconsin - Madison, Madison, WI, United States, ²Electrical and Computer Engineering, University of Wisconsin - Madison, Madison, WI, United States, ³Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ⁴Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States, ⁵Medicine, University of Wisconsin - Madison, Madison, WI, United States, ⁶Emergency Medicine, University of Wisconsin - Madison, Madison, WI, United States

The effects of RF pulse duration on chemical shift encoded MRI (CSE-MRI) methods is a previously unexplored potential confounder for accurate and precise estimation of proton density fat fraction (PDFF) and R2*. Most signal models of CSE-MRI model RF excitation as instantaneous rotation of bulk magnetization; however, instantaneous excitation is not physically realizable. In this work we use Bloch equation simulations to characterize the effect of pulse duration on PDFF and R2* bias. We found that R2* bias was more sensitive than PDFF bias to RF pulse duration and note that clinically meaningful bias can be observed.

This abstract and the presentation materials are available to members only; a login is required.

Join Here