Abstract #3055

Rigid Motion Correction for High Resolution Brain PET/MR Imaging

Mohammad Mehdi Khalighi¹, Mackenzie Carlson², Matthew Spangler-Bickell³, Timothy Deller⁴, Kristen Wangerin⁴, Dan Rettmann⁴, Tim Skloss⁴, Brian Burns⁴, Dawn Holley¹, Kim Halbert¹, Tyler N Toueg⁵, Phillip S DiGiacomo¹, Murat Aksoy⁶, Julian Maclaren⁶, Roland Bammer⁶, Floris Jansen⁴, Fred T. Chin¹, Michael Moseley¹, Greg Zaharchuk¹, Elizabeth Mormino⁵, and Michael Zeineh¹

¹Radiology, Stanford Univ., Stanford, CA, United States, ²Bioengineering, Stanford Univ., Stanford, CA, United States, ³Was with: Nuclear Medicine, IRCCS Ospedale San Raffaele, Milan, Italy, ⁴GE Healthcare, Waukesha, WI, United States, ⁵Neurology, Stanford Univ., Stanford, CA, United States, ⁶HobbitView, San Jose, CA, United States

In a brain PET/MR scan, the PET acquisition is done during the entire exam which typically lasts between 30-60 min. Most subjects, especially patients with a motion disorder or AD, exhibit some degree of motion which results in image blurring, quantitative errors due to mismatched attenuation correction, and mis-registered PET and MR images which limits the advantages of PET reconstruction using anatomical priors. In this study, we describe the benefits of an optical motion tracking technique, which has been recently introduced for PET/MR, to acquire high resolution isotropic PET/MR images.

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