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Abstract #3038

Towards Comprehensive Assessment of Lung Injury Using Multi-Modality Hyperpolarized MRI

Mehrdad Pourfathi1, Hooman Hamedani1,2, Yi Xin1,2, Stephen J Kadlecek1, Ian Duncan1, Maurizio Cereda1,3, Sarmad Siddiqui1, Harrilla Profka1, Luis Loza1, Faraz Amzajerdian 1,2, Tahmina Achekzai1, Kai Ruppert1, Michael Rosalino1, Federico Sertic1,4, Ryan Baron1, Jon Snow1, Yiwen Qian1,2, Gabriel Unger1, Shampa Chatterjee5, and Rahim R. Rizi1
1Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, 3Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States, 4Surgery, University of Pennsylvania, Philadelphia, PA, United States, 5Physiology, University of Pennsylvania, Philadelphia, PA, United States

Hyperpolarized 13C and 129Xe MRI are novel imaging methods that have been used to characterize tissue metabolism and lung function, respectively. In this study, we demonstrate the use of these techniques in tandem in order to characterize lung injury in a porcine model of aspiration pneumonitis.

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