With higher field strength and, thus, better SNR available, 23Na-MRI is becoming increasingly popular in (pre-) clinical studies. Improving accuracy and repeatability will help to translate 23Na-MRI into routine. Therefore, we investigated the effect of respiratory and cardiac gating, as well as the influence of B1-field correction on cardiac total sodium quantification with a 2D radial UTE sequence in mice using a surface coil at 7T. We found that ungated and uncorrected measurements overestimate cardiac sodium concentration. Combined respiratory and cardiac gating and B1-field correction significantly decreased the measured cardiac tissue sodium concentration (-40.6%).
This abstract and the presentation materials are available to members only; a login is required.