Abstract #2942

Lactate change during visual stimuli detected by MEGA-PRESS at 3T

Ya-Tien Liu¹, Dian-Han Yang¹, Cheng-Wen Ko¹, Tzu-Chao Chuang², and Shang-Yueh Tsai^3,4

¹Department of Computer Science and Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, ²Department of Electrical Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, ³Graduate Institute of Applied Physics, National Chengchi University, Taipei, Taiwan, ⁴Research Center of Mind, National Chengchi University, Taipei, Taiwan

In this study, we investigate the feasibility of using MEGA-PRESS to detect Lac response to the visual stimuli in visual cortex in fMRS experiment at 3T. The significant raise in Lac level was found either by averaging the whole fMRS scan or by averaging over the stimuli blocks. Our results show consistency with the published results. More sophisticated approach to analyze fMRS data may be necessary to facilitate reliable metabolic quantification.

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