Abstract #2873

In Situ Quantification of the Longitudinal Relaxation Time of Phophatidylcholine in Human Bile at 7T

Lorenz Pfleger^1,2, Albrecht Ingo Schmid^2,3, Stefan Wampl^2,3, Martin Gajdošík^1,2,4, Siegfried Trattnig^2,5, Michael Krebs¹, and Martin Krššák^1,2,5

¹Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria, ²High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ³Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, ⁴Department of Biomedical Engineering, Columbia University, New York, NY, United States, ⁵Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

This study focuses on the in vivo determination of the longitudinal relaxation time (T₁) of phosphatidylcholine (PtdC) in the gallbladder at 7T and its challenges. In most cases, it was possible to assess T₁ with a 1D-ISIS sequence. In cases where the gallbladder is further away from the coil a STEAM sequence, which does not depend on 180° RF pulses, can be used. The T₁ values of PtdC ranged between 290 and 480ms.

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