This study aimed to investigate the role of multi-echo Dixon technique and IVIM-DWI in assessing vertebral marrow changes among subjects with osteoporosis, osteopenia and normals. The multi-echo Dixon technique and IVIM-DWI were used to evaluate 26 healthy volunteers, 26 osteopenia patients and 24 osteoporosis patients. The FF, D and D* among osteoporosis, osteopenia and normals were significantly different.Furthermore, we found that there was a statistically significant positive correlation between D value and T-score,while the D* value and FF were negatively correlated to the T-score.
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