Abstract #2761

Vertebral Marrow Microenvironment Indexes in Middle-aged and Elderly People with Varying Bone Mineral Density: Functional MRI Evaluation

Jingqi Zhu¹, Xueli Zhang¹, Yun Tu¹, Rui Tang¹, Rui Ji¹, Jilei Zhang², Ting Hua¹, and Guangyu Tang*¹

¹Department of Radiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China, ²Clinical Science, Philips Healthcare, Shanghai, China

Our study found that the differences of the parameters of mDIXON-Quant and IVIM-DWI [T₂*, fat fraction (FF) and f values] among three groups with varying bone mineral density (normal, osteopenic and osteoporotic) were statistically significant. The correlations of the T₂* and FF values with T-score were negative and the correlations of the D* and f values with T-score were positive. Our study implies that mDIXON-Quant and IVIM-DWI techniques were helpful to reflect the changes of vertebral marrow microenvironment of osteoporosis, which may provide valuable information for the assessment of the bone quality.

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