Abstract #2708

Detecting Muscle Activity using a 0.5T Upright Open MRI – A Pilot Study Using a Double Echo Steady State Sequence to Measure T2 in Biceps and Triceps

Noor Shaikh^1,2,3, Andrew Yung⁴, Honglin Zhang⁵, John Street^2,6, Cornelia Laule^2,7,8,9, Thomas Oxland^2,3,6, and David Wilson^2,5,6

¹Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada, ²ICORD, University of British Columbia, Vancouver, BC, Canada, ³Mechanical Engineering, University of British Columbia, Vancouver, BC, Canada, ⁴UBC MRI Research Center, University of British Columbia, Vancouver, BC, Canada, ⁵Centre for Hip Health and Mobility, University of British Columbia, Vancouver, BC, Canada, ⁶Orthopaedics, University of British Columbia, Vancouver, BC, Canada, ⁷Radiology, University of British Columbia, Vancouver, BC, Canada, ⁸Physics & Astronomy, University of British Columbia, Vancouver, BC, Canada, ⁹Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada

We used a 0.5T upright open MRI to investigate T₂ as a marker for muscle activity. Six volunteers’ arms were imaged with a Double Echo Steady State (DESS) sequence while relaxing (30min), following weighted bicep curls, and again after relaxing (20min). Directly after bicep curls T₂ increased (average 41%) in the biceps but not the triceps, then subsequently decreased (average 14%) with relaxing. Intra-rater repeatability was promising. T₂ standard deviation was relatively high, which is likely due to tissue heterogeneity. This preliminary study supports the potential of using DESS in upright open MRI to assess muscle injury or dysfunction.

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